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pentobarbital will lower the level or result of doravirine by impacting hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will minimize the extent or outcome of vardenafil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.pentobarbital will reduce the level or outcome of itraconazole by impacting hepatic/intestin